Xiaoshan Zhu

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Professor

Phone: (775) 682-6298
Email: xzhu@unr.edu
Building:
Room: 337A
Mail stop: 0260
Website:

B. Sreenan, V. Kafil, H. Tanner, S.H.R. Shin, A. Brennan, Y. Tal-Gan, P. Thallapally, Xiaoshan Zhu*, Luminescent ZnO-Carbon Hybrid Nanomaterials: Synthesis, Characterization, Emission Mechanism, and Applications, ACS Applied Optical Materials, 2025, 3(3), 698–711. https://doi.org/10.1021/acsaom.4c00509.
B. Sreenan, V. Kafil, D. Wells, G. Kharal, T. Hunter, A. Gulbag, J. Park, H. Xu, M. Sanad, M. S. Fadali, Y. Jia, Q. Cheng, D. AuCoin, L. Miller, Xiaoshan Zhu*, Development of Time-Resolved Luminescence Measurement Instruments for Biosensing and Bioimaging – An Overview, Measurement: Journal of the International Measurement Confederation, 2025, 25, 117201. https://doi.org/10.1016/j.measurement.2025.117201.
A. Gulbag, M. Huang, B. Rong, B. Sreenan, Xiaoshan Zhu*, A Simple Circuit for Time-Resolved Luminescence (TRL) Measurement Instruments: Demonstration Through a Smartphone-Based TRL Imager for Anticounterfeiting Application, IEEE Sensors Letters, 2025, 9, 3, 5500704. DOI: 10.1109/LSENS.2025.3535901.
V. Kafilǂ, B. Sreenanǂ, S.H.R. Shin, A. Brennan, P. Brett, D. AuCoin, P. Thallapally, Y. Tal-Gan, Xiaoshan Zhu*, Highly Active Carbon-Platinum-Based Nanozymes: Synthesis, Characterization, and Immunoassay Application, ACS Applied Nano Materials, 2024, 7, 28283–28295. https://doi.org/10.1021/acsanm.4c05224. (ǂ equally contributed, co-first authors). https://doi.org/10.1016/j.mehy.2024.111521. (ǂ equally contributed, co-first authors).
V. Kafil, B. Lee, M. Hadj-Nacer, Y. Wang, J. Yoon, M. Greiner, S.H.R. Shin, P. Thallapally, Xiaoshan Zhu*, Hydrogen Sensing in Different Hydrogen-Carrying Gases Using Composites of PdSnO2 and Halloysite Nanotubes, Sensors and Actuators A, 2024, 376, 115622. https://doi.org/10.1016/j.sna.2024.115622.
V. Kafil, B. Sreenan, M. Hadj-Nacer, Y. Wang, J. Yoon, M. Greiner, P. Chu, X. Wang, S. Fadali, Xiaoshan Zhu*, Review of Noble Metal and Metal-Oxide-Semiconductor Based Chemiresitive Hydrogen Sensors, Sensors and Actuators A, 2024, 373, 115440. https://doi.org/10.1016/j.sna.2024.115440.
B. Lee, G. Kharal, B. Sreenan, C. Lin, R. Zeng, C. Fox, P. Ellison, R. Ryan, P. Brett, D. AuCoin, Xiaoshan Zhu*, Alkaline Surface Treatment and Time-Resolved Reading of Mn-Doped Nanocrystal Signal Transducer for Enhanced Bioassay Sensitivity, Journal of Pharmaceutical and Biomedical Analysis, 2023, 238, 115840. https://doi.org/10.1016/j.jpba.2023.115840.
V. Kafil, J. Liles, L. Coello-Poole, B. Lee, A. Sjolund, Y. Wang, J. Yoon, M. Greiner, M. Hadj-Nacer, Xiaoshan Zhu*, Highly Sensitive Detection of Hydrogen Gas Using Nanoporous Composites of Halloysite Nanotubes and Palladium, ACS Applied Electronic Materials, 2023, 5, 5202-5214. DOI:.1021/acsaelm.3c00904.
Y. Chen, J. Wu, S. Zhang, X. Zhu, B. Zou, R. Zeng, Effective Energy Transfer Boosts Emission of Rare-Earth Double Perovskites: The Bridge Role of Sb(III) Doping, ACS Journal of Physical Chemistry Letters, 2023, 14, 7108−7117. DOI: 10.1021/acs.jpclett.3c01825.
B. Sreenan, B. Lee, L. Wan, R. Zeng, J. Zhao, Xiaoshan Zhu*, Review of Development of Mn Doped Nanocrystals for Time-Resolved Luminescence Biosensing/Imaging, ACS Applied Nano Materials, 2022. DOI: 10.1021/acsanm.2c04337.
Y. Chen, R. Zeng, Q. Wei, S. Zhang, Y. Wang, C. Chen, Xiaoshan Zhu, S. Cao, B. Zou, J. Zhang, Competing-Energy-Transfer Modulated Dual Emission in Mn2+-Doped Cs2NaTbCl6 Rare-Earth Double Perovskites, Journal of Physical Chemistry Letters, 2022, 13, 8529-8536. DOI: 10.1021/acs.jpclett.2c02491.
T. Chang, Q. Wei, Z. Wang, Y. Gao, B. Lian, Xiaoshan Zhu, S. Cao, J. Zhao, B. Zou, R. Zeng, Phase-Selective Solution Synthesis of Cd-Based Perovskite Derivatives and Their Structure/Emission Modulation, Journal of Physical Chemistry Letters, 2022, 13, 3682–3690, DOI: 10.1021/acs.jpclett.2c00863.
B. Lee, S. Tian, G. Xiong, Y. Yang, Xiaoshan Zhu*, Solvothermal Synthesis of Transition-metal (Fe/Cu) and Nitrogen Co-Doped Carbon Nanomaterials: Comparing Their Peroxidase-like Properties, Journal of Nanoparticle Research, 2022, 24:85, DOI:10.1007/s11051-022-05470-y.
T. Hegseth, B. Lee, D. Aucoin, Xiaoshan Zhu*, A Compact and Sensitive Time-Resolved-Optical-Reader for Bioassay Using Low-Energy Excitable and Long-Lived-Fluorescence Nanolabels, IEEE Sensors Letters, 2022, 6, 4, 5000304, DOI:10.1109/LSENS.2022.3159761.
B. Lee, T. Hegseth, Y. Song, J. Zhao, Xiaoshan Zhu*, Mn-Doped AgZnInS/ZnS Nanocrystals (NCs): Effects of Zn Etching on the NC Optical Properties, Optical Materials, 2022, 123, 111941. DOI:10.1016/j.optmat.2021.111941.
V. G. Demillo, Xiaoshan Zhu*, Composites and Compositions for Therapeutic Use and Methods of Making and Using The Same, US Patent No. US 10,994,031, B2, May 4, 2021. (83 Pages)
B. Gallian, G. Dong, Xiaoshan Zhu*, A Compact Time-Gated Instrument for QDs with Low Excitation Energy and Millisecond Fluorescence Lifetime as Signal Reporters, and Its Detection Application, Review of Scientific Instruments, 2019, 90, 104701, DOI: 10.1063/1.5111147.
M. S. Zaeimian, B. Gallian, C. Harrison, Y. Wang, J. Zhao, Xiaoshan Zhu*, Mn Doped AZIS/ZnS Nanocrystals (NCs): Effects of Ag and Mn on NC Optical Properties, Journal of Alloys and Compounds, 2018, 765, 236-244.
S. Chen, M. S. Zaeimian, J. Monteiro, J. Zhao, A. G. Mamalis, A. de Bettencourt-Dias, Xiaoshan Zhu, Mn Doped AIZS/ZnS Nanocrystals: Synthesis and Optical Properties, Journal of Alloys and Compounds, 2017, 725, 1077-1083.
Xiaoshan Zhu, Low Cost, Efficient Dual Signal Amplification for Bioassays, US Patent No. US 9,482,616, B2, Nov 1, 2016. (53 Pages)
S. Chen, M. Ahmadiantehrani, J. Zhao, S. Zhu, A. G. Mamalis, Xiaoshan Zhu*, Heat-up Synthesis of Ag-In-S and Ag-In-S/ZnS Nanocrystals: Effect of Indium Precursors on Their Optical Properties, Journal of Alloys and Compounds, 2016, 665, 137–143.
V. G. Demillo, Xiaoshan Zhu, Zwitterionic Amphiphile Coated Magnetofluorescent Nanoparticles – Synthesis, Characterization and Tumor Cell Targeting, Journal of Materials Chemistry B, 2015, 3, 8328-8336.
R. Shrake, V. G. Demillo, M. Ahmadiantehrani, N. G. Publicover, K. W. Hunter Jr., Xiaoshan Zhu*, Facilitated Preparation of Bioconjugatable Zwitterionic Quantum Dots Using Dual-Lipid Encapsulation, Journal of Colloid and Interface Science. 2015, 437, 140–146.
C. Cowles, Xiaoshan Zhu*, Dual Signal Amplification for Bioassays Using Ion Release of Nanolabels and Ion-Activated Enzyme Kinetics, Analyst, 137, 4815 – 4821, 2012.
C. Cowles, Xiaoshan Zhu*, Sensitive Detection of Cardiac Biomarker Using ZnS Nanoparticles as Novel Signal Transducers, Biosensors and Bioelectronics, 30, 342-346, 2011.
C. Cowles, N. Publicover, Xiaoshan Zhu*, Fluorescence Signal Transduction Mechanism for Immunoassay Based on Zinc Ion Release from ZnS Nanocrystals, Analyst, 136, 2975 – 2980, 2011.
Xiaoshan Zhu*, D. Duan, S. Madsen, N. Publicover, Compatibility of Quantum Dots with Immunobuffers, and its Effect on Signal/Background of Quantum Dot-based Immunoassay, Analytical and Bioanalytical Chemistry, 369, 1345-1353, 2010.
Xiaoshan Zhu*, D. Duan, N. Publicover, Magnetic Bead Based Assay for C-Reactive Protein Using Quantum-Dot Fluorescence Labeling and Immunoaffinity Separation, Analyst, 135, 381-389, 2010.
A. Bange, J. Tu, Xiaoshan Zhu, C. Ahn, B. Halsall, W. Heineman, Electrochemical Detection of MS2 Phage Using a Bead-based Immunoassay and a NanoIDA, Electroanalysis, 19, 2202-2207, 2007.
Xiaoshan Zhu, J. W. Choi, and C. H. Ahn, A New Dynamic Electrochemical Transduction Mechanism for Interdigitated Array Microelectrodes, Lab Chip, 4, 581 – 587, 2004.

Research interests

New chemical/physical properties,including quantum effects of materials and their biomedical applications
Biosensors, electrochemical sensors and gas sensors
Time-resolved luminescence biosensing/imaging
Wireless-based sensors, sensor networks and sensing data analytics
Integrated sensor systems for point-of-care diagnosis or in-field testing
Electro-optical systems using advanced photonics and electronics for highly sensitive and accurate sensing/imaging
Development, evaluation and application of sensors in healthcare, environmental water/air monitoring, food safety, agriculture, etc.

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Xiaoshan Zhu

Education

Journal Articles and Patents (* presents the corresponding authorship or inventorship)